Effect of Vitamin D Supplementation on Progression of Knee Pain and Cartilage Volume Loss in Patients With Symptomatic Osteoarthritis
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Physician and Sportsmedicine:Volume 41 No. 3
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PRACTICE PEARL:Osteoarthritis is a widespread and significant disorder. Correction of vitamin D deficiency in patients with significant osteoarthritis of the knee did not result in improvement of pain symptoms or in preservation of cartilage in the knee space.
Original article: McAlindon T, LaValley M, Schneider E, et al. Effect of vitamin D supplementation on progression of knee pain and cartilage volume loss in patients with symptomatic osteoarthritis: a randomized controlled trial. JAMA. 2013;309(2):155–162.1